SMP-300

The World's First Totally Implantable, Programmable Micro Infusion Pump for Mouse Animal Model Infusion.


This implantable infusion pump uses a patented, microprocessor controlled peristalsis mechanism for accurate controlled flow. It is the only implantable and programmable pump for mice. iPRECIO can infuse fluids continuously at accurate low flow rate via software programming and it can be refilled via a percutaneously accessible port. 

 iprecio finger

 

Implantable

The pump can be completely implanted in small laboratory animals subcutaneously. Thus, the animal moves freely without any restrain (i.e. tethering) during drug infusion. Additionally, infection risk is reduced, and the animal is likely to be significantly less stressed than in a tethered infusion model.

 

Refillable

You can replenish any medical fluid in the pump via percutaneous access to the pump refill septum and reservoir after implantation of the pump. So, long-term drug infusion can continue until the installed battery life has run out. The reservoir is elastic and configured in such geometry as to allow gentle palpation to confirm an approximate level of fluid in the reservoir.

 

Programmable      

In the easy to use state-of-the-art iPRECIO software, header information along with infusion profile details are entered and ultimately downloaded to the pump's flash memory. Start Time, End Time, Flow-rate (0.0µl/hour to 10.0µl/hour), and infusion profiles maybe programmed. These profiles include sustained release, modified release, chrono release and pulsatile release. A total of 16 steps with repeat function allow both complex and simple infusion profiles to be programmed.

 

A recovery period may also be programmed using the Keep Vein Open Function (KVO) where saline is initially filled in the reservoir. A dead volume flushing function also ensures that the test compound reaches the animal at the programmed time point.

 

Wireless

SMP-300 Micro Infusion Pump allows in-vivo re-programming for maximum flexibility. If no effect is detected, in addition to refilling with a higher concentration TA/drug, reprogramming to higher flow-rate is possible.

 

Precision

The technology driving the infusion is a patented "Rotary Finger" method. This method is a unique form of peristalsis. The precise "micro-stick" pushes a rubber tube in the pump in a uniform and sequential manner. The accuracy of iPRECIO is +/-5%.

iprecio precision

SMP-300

Features

  • Accurate patented Rotary Finger Method
  • Factory tested and calibrated
  • Better than +/-5% accuracy
  • 0 µl/hour - 10.0 µl/hour in 0.1μl/hour steps
  • 101 discreet infusion flow-rates
  • Programmable infusions protocols
  • Totally implanted in subcutaneous space
  • Refillable reservoir percutaneously via refill port
  • With iPRECIO® catheters, test your drug's effects nearly anywhere
  • Easy to use state of the art software
Battery LifePump StructureSpecificationOrder
Infusion Method Rotary Finger Method (patented peristalsis)
Reservoir 130μL Built-in Elastic Reservoir (Medical Grade SEBS)
Tubing Inner Tubing : (Material)Medical Grade SEBS
Outer Tubing : (Material)Medical Grade SEBS (3Fr)
(Size) Inner Diameter :0.55mm / Length :approx. 140mm
Refill Port φ2mm refill port is on the top of the pump.
Data Communication Wireless (Frequency : 915MHz – 928MHz *North America)
Communication Distance :5 m range from the data communication device and pump.
Antenna A wire anntena attached to the pump (length: approx. 50mm, not removable) *Material of Wire anntena: Titanium (φ0.1mm), Coated by 1.2 Fr Polyurethane Tubing
Range of Flow Rate Range of Flow Rate(FR)0.0 - 10.0µL/hr (Resolution:0.1µL/hr) discharge volume by 1 time rotation of the cam:3.4µL
Accuracy ±5% (under 0 - 80cmH2O pressure)
Battery Life Continuous driving life : FR 0.1µL/hr:19 days FR 10.0µL/hr:1 week
Activation Method Pump is activated by pressing down the power button placed on the bottom of the pump. On only. Cannot be switched OFF.
Size 24.8(L) x 15.0(W) x 7.2 (H) mm (not including outer catheter and wire anntena)
Weight 3.3g (including outer catheter and wire anntena)
Volume 2.15cc
Type of Usage Disposable
Package Sterilized blister package (5pcs/box)
Sterilization 2 years

SMP-300 Pump Structure

iprecio pump structure

Preliminary Infusion Time
Flow RateDays (approx)  
10μL/hr 7 days
1μL/hr 16 days
0 & 0,1μL/hr 19 days