Availability date:
The World's First Totally Implantable, Programmable Micro Infusion Pump for Mouse Animal Model Infusion. This implantable infusion pump uses a patented, microprocessor controlled peristalsis mechanism for accurate controlled flow. It is the only implantable and programmable pump for mice. iPRECIO can infuse fluids continuously at accurate low flow rate via software programming and it can be refilled via a percutaneously accessible port.
Implantable
The pump can be completely implanted in small laboratory animals subcutaneously. Thus, the animal moves freely without any restrain (i.e. tethering) during drug infusion. Additionally, infection risk is reduced, and the animal is likely to be significantly less stressed than in a tethered infusion model.
Refillable
You can replenish any medical fluid in the pump via percutaneous access to the pump refill septum and reservoir after implantation of the pump. So, long-term drug infusion can continue until the installed battery life has run out. The reservoir is elastic and configured in such geometry as to allow gentle palpation to confirm an approximate level of fluid in the reservoir.
Programmable
In the easy to use state-of-the-art iPRECIO software, header information along with infusion profile details are entered and ultimately downloaded to the pump's flash memory. Start Time, End Time, Flow-rate (0.0µl/hour to 10.0µl/hour), and infusion profiles maybe programmed. These profiles include sustained release, modified release, chrono release and pulsatile release. A total of 16 steps with repeat function allow both complex and simple infusion profiles to be programmed.
A recovery period may also be programmed using the Keep Vein Open Function (KVO) where saline is initially filled in the reservoir. A dead volume flushing function also ensures that the test compound reaches the animal at the programmed time point.
Wireless
SMP-300 Micro Infusion Pump allows in-vivo re-programming for maximum flexibility. If no effect is detected, in addition to refilling with a higher concentration TA/drug, reprogramming to higher flow-rate is possible.
Precision
The technology driving the infusion is a patented "Rotary Finger" method. This method is a unique form of peristalsis. The precise "micro-stick" pushes a rubber tube in the pump in a uniform and sequential manner. The accuracy of iPRECIO is +/-5%.
Flow Rate | Days (approx) |
---|---|
10μL/hr | 7 days |
1μL/hr | 16 days |
0 & 0,1μL/hr | 19 days |
Dimensions | 24.8 x 15.0 x 7.2 mm (not including outer catheter and wire anntena) |
Weight | 3.3 grams |
Accuracy | ±5% (under 0 - 80 cmH2O pressure) |
Battery | Continuous driving life : FR 0.1µL/hr:19 days FR 10.0µL/hr:1 week |
Type of Usage | Disposable |
Infusion Method | Rotary Finger Method (patented peristalsis) |
Reservoir | 130μL Built-in Elastic Reservoir (Medical Grade SEBS) |
Tubing | Medical Grade SEBS |
By clicking any link on this page you are giving your consent for us to set cookies.
What Are Cookies
As is common practice with almost all professional websites this site uses cookies, which are tiny files that are downloaded to your computer, to improve your experience. This page describes what information they gather, how we use it and why we sometimes need to store these cookies. We will also share how you can prevent these cookies from being stored however this may downgrade or 'break' certain elements of the sites functionality.
For more general information on cookies see the Wikipedia article on HTTP Cookies.
How We Use Cookies
We use cookies for a variety of reasons detailed below. Unfortunately in most cases there are no industry standard options for disabling cookies without completely disabling the functionality and features they add to this site. It is recommended that you leave on all cookies if you are not sure whether you need them or not in case they are used to provide a service that you use.
Disabling Cookies
You can prevent the setting of cookies by adjusting the settings on your browser (see your browser Help for how to do this). Be aware that disabling cookies will affect the functionality of this and many other websites that you visit. Disabling cookies will usually result in also disabling certain functionality and features of the this site. Therefore it is recommended that you do not disable cookies.
The Cookies We Set
If you create an account with us then we will use cookies for the management of the signup process and general administration. These cookies will usually be deleted when you log out however in some cases they may remain afterwards to remember your site preferences when logged out.
We use cookies when you are logged in so that we can remember this fact. This prevents you from having to log in every single time you visit a new page. These cookies are typically removed or cleared when you log out to ensure that you can only access restricted features and areas when logged in.
This site offers newsletter or email subscription services and cookies may be used to remember if you are already registered and whether to show certain notifications which might only be valid to subscribed/unsubscribed users.
This site offers e-commerce or payment facilities and some cookies are essential to ensure that your order is remembered between pages so that we can process it properly.
In order to provide you with a great experience on this site we provide the functionality to set your preferences for how this site runs when you use it. In order to remember your preferences we need to set cookies so that this information can be called whenever you interact with a page is affected by your preferences.
Third Party Cookies
In some special cases we also use cookies provided by trusted third parties. The following section details which third party cookies you might encounter through this site.
This site uses Google Analytics which is one of the most widespread and trusted analytics solution on the web for helping us to understand how you use the site and ways that we can improve your experience. These cookies may track things such as how long you spend on the site and the pages that you visit so we can continue to produce engaging content.
For more information on Google Analytics cookies, see the official Google Analytics page.
From time to time we test new features and make subtle changes to the way that the site is delivered. When we are still testing new features these cookies may be used to ensure that you receive a consistent experience whilst on the site whilst ensuring we understand which optimisations our users appreciate the most.
More Information
Hopefully that has clarified things for you and as was previously mentioned if there is something that you aren't sure whether you need or not it's usually safer to leave cookies enabled in case it does interact with one of the features you use on our site.
However if you are still looking for more information then you can contact us through one of our preferred contact methods. This Cookies Policy was created with the help of the CookiePolicyGenerator.com
Email: agnthos@agnthos.se